Spontaneous and Induced Mutation in Mycobacterium avium
نویسندگان
چکیده
منابع مشابه
Differential responses of bovine macrophages to Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium.
Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium are antigenically and genetically similar organisms; however, they differ in their virulence for cattle. M. avium subsp. paratuberculosis causes a chronic intestinal infection leading to a chronic wasting disease termed paratuberculosis or Johne's disease, whereas M. avium subsp. avium causes only a transient infec...
متن کاملMolecular and cellular mechanisms of Mycobacterium avium-induced thymic atrophy.
Thymic atrophy has been described as a consequence of infection by several pathogens and shown to be induced through diverse mechanisms. Using the mouse model of Mycobacterium avium infection, we show in this study that the production of NO from IFN-γ-activated macrophages plays a major role in mycobacterial infection-induced thymic atrophy. Our results show that disseminated infection with a h...
متن کاملDoxycycline Attenuated Mycobacterium avium Induced Inflammation in Mice
Mycobacterium avium causes chronic and progressive respiratory infection. A therapeutic regimen including clarithromycin, rifampin and ethambutol has been commonly employed, however, the effect of such antibacterial therapy is often unsatisfactory. Doxycycline is an antibiotic known to have immuno-modulating effects as well as antibacterial activity. In this study, we investigated the effect of...
متن کاملPreparation and Purification of Polyclonal Antibodies against Mycobacterium Avium Paratuberculosis Antigens in Rabbit
Background and Objective: Johne’s disease is the chronic granulomatous enteritis of ruminants, and a major health hazard worldwide. In recent years, researchers have focused on mycobacterium avium subsp. paratuberculosis (MAP) antigens in diagnostic tests. Identification of antibodies against MAP antigens is, therefore, effective for the diagnosis or preparation of vaccine. The aim of this stud...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1970
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.2.3.223-228.1970